Skip to main content

Death rate from Parkinson’s rising in US

Death rate from Parkinson’s rising in US

A new study shows that in the last two decades the death rate from Parkinson’s disease has risen about 63% in the United States. The research is published in the October 27, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found that the death rate was twice as high in men as in women, and there was a higher death rate in white people than other racial/ethnic groups.

“We know that people are living longer and the general population is getting older, but that doesn’t fully explain the increase we saw in the death rate in people with Parkinson’s,” study author Wei Bao, MD, PhD, who conducted the research at the University of Iowa in Iowa City. “Understanding why more people are dying from this disease is critical if we are going to reverse the trend.”

The study looked at a national death registry that included 479,059 people who died of Parkinson’s between 1999 and 2019.

After adjusting for age, researchers found that the number of people who died from the disease increased from 5.4 per 100,000 people in 1999 to 8.8 per 100,000 people in 2019. The average annual increase was 2.4%.

Researchers found mortality increased significantly across all age groups, both sexes, various racial and ethnic groups and different urban-rural classifications. However, death rates were twice as high in men as in women. Bao says one possible explanation for this sex difference is that estrogen, which leads to higher dopamine levels in parts of the brain that control motor responses, may protect women from developing Parkinson’s.

White people were more likely to die from Parkinson’s than other racial and ethnic groups. In 2019, the death rate for white people was 9.7 per 100,000 people, followed by Hispanic people, at 6.5 per 100,000 people, and non-Hispanic Black people, at 4.7 per 100,000 people. Bao said previous studies have shown that compared to white people, Black and Hispanic people are less likely to see an outpatient neurologist, due to socioeconomic barriers, suggesting that white people may have a higher chance of receiving a Parkinson’s diagnosis.

“It’s important to continue to evaluate long-term trends in Parkinson’s death rates,” Bao said. “This can inform future research that may help pinpoint why more people are dying of the disease. Also, updating vital statistics about Parkinson’s death rates may be used for priority setting and financing of health care and policy.”

A limitation of the study is that only one underlying cause of death was recorded on each death certificate, so only people who were recorded as having died of Parkinson’s were included in the study. This may not accurately reflect the prevalence of the disease as a cause of death.

Learn more about Parkinson’s disease at BrainandLife.org, home of the American Academy of Neurology’s free patient and caregiver magazine focused on the intersection of neurologic disease and brain health. Follow Brain & Life® on Facebook, Twitter and Instagram.

When posting to social media channels about this research, we encourage you to use the hashtags #Neurology and #AANscience.

The American Academy of Neurology is the world’s largest association of neurologists and neuroscience professionals, with over 36,000 members. The AAN is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, migraine, multiple sclerosis, concussion, Parkinson’s disease and epilepsy.

For more information about the American Academy of Neurology, visit AAN.com or find us on Facebook, Twitter, Instagram, LinkedIn and YouTube.



from ScienceBlog.com https://ift.tt/3CqvWVc
Labels:

Comments

Post a Comment

Popular posts from this blog

Wiggling worms suggest link between vitamin B12 and Alzheimer’s

Worms don’t wiggle when they have Alzheimer’s disease. Yet something helped worms with the disease hold onto their wiggle in Professor Jessica Tanis’s lab at the University of Delaware. In solving the mystery, Tanis and her team have yielded new clues into the potential impact of diet on Alzheimer’s, the dreaded degenerative brain disease afflicting more than 6 million Americans. A few years ago, Tanis and her team began investigating factors affecting the onset and progression of Alzheimer’s disease. They were doing genetic research with  C. elegans , a tiny soil-dwelling worm that is the subject of numerous studies. Expression of amyloid beta, a toxic protein implicated in Alzheimer’s disease, paralyzes worms within 36 hours after they reach adulthood. While the worms in one petri dish in Tanis’s lab were rendered completely immobile, the worms of the same age in the adjacent petri dish still had their wiggle, documented as “body bends,” by the scientists. “It was an observa...
Post a Comment
Read more

‘Massive-scale mobilization’ necessary for addressing climate change, scientists say

A year after a global coalition of more than 11,000 scientists declared a climate emergency, Oregon State University researchers who initiated the declaration released an update today that points to a handful of hopeful signs, but shares continued alarm regarding an overall lack of progress in addressing climate risks. “Young people in more than 3,500 locations around the world have organized to push for urgent action,” said Oregon State University’s William Ripple, who co-authored “The Climate Emergency: 2020 in Review,” published today in Scientific American. “And the Black Lives Matter movement has elevated social injustice and equality to the top of our consciousness. “Rapid progress in each of the climate action steps we outline is possible if framed from the outset in the context of climate justice – climate change is a deeply moral issue. We desperately need those who face the most severe climate risks to help shape the response.” One year ago, Ripple, distinguished profess...
Post a Comment
Read more

Ancient Shell Sounds

Abandoned at the mouth of your shelter you quivered apprehensively at our approach, crying out to be held as we proclaimed the exception of your discovery. Sighing wearily as we consigned you to the dusty silence of our archives. But now When I hold you in my hands, I see the face of your purposefully speckled complexion. When I lift you to my ear, I hear the sound of an ancient sea lapping at your shores. When I place you at my lips, I feel the heartbeat of your creator pulsing to my breath. I close my eyes, as you call out to all that you have lost. The shell that was recovered from the Marsoulas cave in the Pyrenees of France (Image Credit: C. Fritz, Muséum d’Histoire naturelle de Toulouse). This poem is inspired by recent research , which has discovered that a large seashell that sat in a French museum for decades is actually a musical instrument used around 18,000 years ago. In 1931, researchers working in southern France unearthed a large seashell at the entr...
Post a Comment
Read more